Google has introduced SynthID Bio, which embeds digital watermarks into biological codes and enables verification in digital models and on synthetic proteins without compromising biological function. In wet-lab tests on three target proteins — VEGF-A, SARS-CoV-2 spike protein RBD, and PD-L1 — watermarked designs performed on par with unwatermarked versions, yielding the first watermarked protein binders with biological function. The technology also fine-tunes the AlphaFold 3 diffusion network and has been integrated into the genomic model Evo 2 to watermark phage genomes.